CarSpecFix
OBD-II trouble code

P0300: Random/Multiple Cylinder Misfire Detected, causes & can you keep driving?

Quick answer

What it means
Random/Multiple Cylinder Misfire Detected[1]
Wording from VW TSB 01-16-13 Engine Misfire Diagnostic Aid, p.1
Can I keep driving?
Under certain conditions, the dashboard light will blink or flash. This indicates a rather severe level of engine misfire. When this occurs, the driver should reduce speed and seek service as soon as possible.[2]
U.S. EPA Fact Sheet EPA 420-F-97-003 (May 1997), Frequently Asked Questions About On-Board Diagnostics, p.2 · applies to all OBD-II vehicles
It is important to note that an illuminated dashboard light, as described here, is intended to inform the driver of the need for service, NOT of the need to stop the vehicle. However, service should be sought as soon as possible.[2]
U.S. EPA Fact Sheet EPA 420-F-97-003 (May 1997), Frequently Asked Questions About On-Board Diagnostics, p.2 · applies to all OBD-II vehicles
2023 Ford only If it flashes, engine misfire could be occurring. Increased exhaust gas temperatures could damage the catalytic converter or other vehicle components. Drive in a moderate fashion (avoid heavy acceleration and deceleration) and have your vehicle checked as soon as possible.[3]
Toyota only Malfunction indicator lamp ... Indicates a malfunction in: The electronic engine control system; The electronic throttle control system; or The electronic automatic transmission control system → Have the vehicle inspected by your Toyota dealer immediately.[4]
How urgent?
Not rated
Severity is rated only when a source states it.
Shop visit or check it yourself first?
Not yet verified — source pending
Last verified 2026-10-15Report a data error

Possible causes

Each cause comes from a manufacturer document and applies to the models listed. Your vehicle may differ.

  1. VW's service bulletin (VW 01-16-13, p.1) [1]
    Low fuel level can cause misfire codes (with P1250)
  2. VW's service bulletin (VW 01-16-13, p.2) [1]
    P0300 alone is not a reason to replace all injectors, plugs or coils
  3. GM's service bulletin (GM 15-06-01-002M, p.1) [5]
    AFM lifter collapsed/stuck, lifter locking pin damage from oil aeration, bent pushrod

Sources

  1. VW TSB 01-16-13 Engine Misfire Diagnostic Aid, p.1, retrieved 2026-10-15
  2. U.S. EPA Fact Sheet EPA 420-F-97-003 (May 1997), Frequently Asked Questions About On-Board Diagnostics, p.2, retrieved 2026-10-15
  3. Ford 2023 Motorhome (chassis) Owner's Manual, hosted by NHTSA in investigation PE24-023, PDF p.33 (Instrument Cluster), retrieved 2026-10-15
  4. 2022 Toyota Camry Owner's Manual OM06244U, p.528, retrieved 2026-10-15
  5. GM 15-06-01-002M, p.1, retrieved 2026-10-15

General information from manufacturer documents, not professional mechanical advice. See Data sources.